The Influence of Detoxification Agents on the Intensity of Side Effects Caused by Medium-high Doses of Methotrexate in Children with Acute Lymphoblastic Leukemia: Case Series
نویسندگان
چکیده
Corresponding author: Assist. Boris Ž. MILIJAŠEVIĆ, MD, PhD Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, 3 Hajduk Veljkova Str., 21000 Novi Sad, Serbia E-mail: [email protected] © Th e Se rb ia n M ed ic al S oc ie ty 2 01 4 The Influence of Detoxification Agents on the Intensity of Side Effects Caused by Medium-high Doses of Methotrexate in Children with Acute Lymphoblastic Leukemia: Case Series
منابع مشابه
Medium and High-Dose Methotrexate-Induced Toxicity in Children with Acute Lymphoblastic Leukemia
Background: Methotrexate has an important role in treatment of acute leukemia. We measured methotrexate level in CSF and blood of children with acute lymphoblastic leukemia to determine complications and outcomes. Materials and Methods: One hundred and twenty patients (73 male, 47 female), with mean age at diagnosis of 6.1 years (11mo_15years) entered the study. Patients were divided into two...
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Abstact：objective To investigate acute kidney injury (AKI) in children with acute lymphoblastic leukemia (ALL) who received high dose methotrexate (MTX) chemotherapy and explore the corresponding treatment. Methods 180 children who received high dose MTX chemotherapy were observed with serum MTX concentration and serum creatinine. Patients with AKI of stage 3 or poor response to conventional tr...
متن کاملMonitoring and treatment of acute kidney injury in children with acute lymphoblastic leukemia after high dose methotrexate chemotherapy
Abstact：objective To investigate acute kidney injury (AKI) in children with acute lymphoblastic leukemia (ALL) who received high dose methotrexate (MTX) chemotherapy and explore the corresponding treatment. Methods 180 children who received high dose MTX chemotherapy were observed with serum MTX concentration and serum creatinine. Patients with AKI of stage 3 or poor response to conventional tr...
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